Solution phase parallel synthesis and evaluation of MAPK inhibitory activities of close structural analogues of a Ras pathway modulator

Solution phase parallel synthesis and evaluation of MAPK inhibitory activities of close structural analogues of a Ras pathway modulator Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors Design, synthesis, and biological evaluation of new B-RafV600E kinase inhibitors Discovery of N-(benzyloxy)-1,3-diphenyl-1H-pyrazole-4-carboxamide derivatives as potential antiproliferative agents by inhibiting MEK Probing a 3,4′-bis-guanidinium diaryl derivative as an allosteric inhibitor of the Ras pathway Design and Synthesis of Orally Bioavailable Benzimidazoles as Raf Kinase Inhibitors Recent advances of RAF (rapidly accelerated fibrosarcoma) inhibitors as anti-cancer agents A novel series of p38 MAP kinase inhibitors for the potential treatment of rheumatoid arthritis Design and Optimization of Potent and Orally Bioavailable Tetrahydronaphthalene Raf Inhibitors Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity