Metabotropic Glutamate Receptors: Novel Targets for Drug Development

Metabotropic Glutamate Receptors: Novel Targets for Drug Development New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III Ligands for Glutamate Receptors:  Design and Therapeutic Prospects Homology Modeling of Metabotropic Glutamate Receptors. (mGluRs) Structural Motifs Affecting Binding Modes and Pharmacological Profile of mGluR1 Agonists and Competitive Antagonists Agonist Selectivity of mGluR1 and mGluR2 Metabotropic Receptors: A Different Environment but Similar Recognition of an Extended Glutamate Conformation Prospects for Metabotropic Glutamate 1 Receptor Antagonists in the Treatment of Neuropathic Pain Common and Selective Molecular Determinants Involved in Metabotopic Glutamate Receptor Agonist Activity A highly selective agonist for the metabotropic glutamate receptor mGluR2 Synthesis and biological evaluation of aryl isoxazole derivatives as metabotropic glutamate receptor 1 antagonists: A potential treatment for neuropathic pain Pharmacophore Models of Group I and Group II Metabotropic Glutamate Receptor Agonists. Analysis of Conformational, Steric, and Topological Parameters Affecting Potency and Selectivity