Glycosidase inhibition by 1-glycosyl-4-phenyl triazoles
Bioorganic & Medicinal Chemistry Letters
2005.0
Abstract
1-Glycosyl-4-phenyl triazoles have been prepared via a copper-mediated [3+2] cycloaddition of glycosyl azides with phenylacetylene. These triazoles have been evaluated for their ability to inhibit the enzymatic activity of glycosidases.