Glycosidase inhibition by 1-glycosyl-4-phenyl triazoles

Bioorganic & Medicinal Chemistry Letters
2005.0

Abstract

1-Glycosyl-4-phenyl triazoles have been prepared via a copper-mediated [3+2] cycloaddition of glycosyl azides with phenylacetylene. These triazoles have been evaluated for their ability to inhibit the enzymatic activity of glycosidases.

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