Dermorphin and Deltorphin Glycosylated Analogues:  Synthesis and Antinociceptive Activity after Systemic Administration

Journal of Medicinal Chemistry
1999.0

Abstract

In the present paper we describe the synthesis of some dermorphin and deltorphin analogues beta-O- and alpha-C-glycosylated on the C-terminal amino acid residue and report their opioid receptor affinity and selectivity as well as their analgesic potency after subcutaneous injection in mice.

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