Discovery of a Bulky 2-tert-Butyl Group Containing Primaquine Analogue That Exhibits Potent Blood-Schizontocidal Antimalarial Activities and Complete Elimination of Methemoglobin Toxicity

Discovery of a Bulky 2-tert-Butyl Group Containing Primaquine Analogue That Exhibits Potent Blood-Schizontocidal Antimalarial Activities and Complete Elimination of Methemoglobin Toxicity 2- tert -Butyl-8-Quinolinamines Exhibit Potent Blood Schizontocidal Antimalarial Activity via Inhibition of Heme Crystallization Antimalarials. 13. 5-Alkoxy analogs of 4-methylprimaquine Antimalarials. 14. 5-(Aryloxy)-4-methylprimaquine analogs. A highly effective series of blood and tissue schizonticidal agents 4-Substituted 5-[m-(trifluoromethyl)phenoxy]primaquine analogs as potential antimalarial agents Synthesis and evaluation of naphthyridine compounds as antimalarial agents Sulfur-interrupted 8-amino side chain analogs of 4-methyl-5-[m-(trifluoromethyl)phenoxy]primaquine as potential antimalarial agents Antimalarials. 10. Synthesis of 4-substituted primaquine analogs as candidate antimalarials Primaquine revisited six decades after its discovery Synthesis of certain hydroxy analogs of the antimalarial drug primaquine and their in vitro methemoglobin-producing and glutathione-depleting activity in human erythrocytes