Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment

Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment Tubulin inhibitors. Synthesis and biological activity of HTI-286 analogs with B-segment heterosubstituents Synthesis and Biological Activity of Analogues of the Antimicrotubule AgentN,β,β-Trimethyl-<scp>l</scp>-phenylalanyl-N-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]-N¹,3-dimethyl-<scp>l</scp>-valinamide (HTI-286) Tubulysin analogs incorporating desmethyl and dimethyl tubuphenylalanine derivatives Synthesis of new bioisosteric hemiasterlin analogues with extremely high cytotoxicity Synthesis of new simplified hemiasterlin derivatives with α,β-unsaturated carbonyl moiety Synthesis and Antimitotic/Cytotoxic Activity of Hemiasterlin Analogues Cytotoxic and tubulin-interactive hemiasterlins from Auletta sp. and Siphonochalina spp. sponges Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents—synthesis, antiproliferative activity and inhibition of tubulin polymerization Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway