Novel spiroanellated 1,2,4-trioxanes with high in vitro antimalarial activities

Novel spiroanellated 1,2,4-trioxanes with high in vitro antimalarial activities Spiro and Dispiro-1,2,4-trioxolanes as Antimalarial Peroxides:  Charting a Workable Structure−Activity Relationship Using Simple Prototypes Photo-Oxygenation of geraniol: synthesis of a novel series of hydroxy-functionalized anti-malarial 1,2,4-trioxanes 3-Alkoxy-1,2-Dioxolanes: Synthesis and Evaluation as Potential Antimalarial Agents Orally Active 1,2,4-Trioxanes:  Synthesis and Antimalarial Assessment of a New Series of 9-Functionalized 3-(1-Arylvinyl)-1,2,5-trioxaspiro[5.5]undecanes against Multi-Drug-Resistant Plasmodium yoelii nigeriensis in Mice Geraniol-derived 1,2,4-Trioxanes with potent in-vivo antimalarial activity Orally active amino functionalized antimalarial 1,2,4-trioxanes 8-(1-Naphthalen-2-yl-vinyl)-6,7,10-trioxaspiro (4.5) decane, a new 1,2,4-trioxane effective against rodent and simian malaria Orally Active Antimalarial 3-Substituted Trioxanes:  New Synthetic Methodology and Biological Evaluation Two-Step Synthesis of Achiral Dispiro-1,2,4,5-tetraoxanes with Outstanding Antimalarial Activity, Low Toxicity, and High-Stability Profiles