Synthesis and biological evaluation of novel bisheterocycle-containing compounds as potential anti-influenza virus agents

Bioorganic & Medicinal Chemistry Letters
2005.0

Abstract

A series of novel 4,2-bisheterocycle tandem derivatives consisting of a methyloxazole and thiazole subunit were synthesized. Many compounds were found to inhibit human influenza A virus. Several analogues exhibited moderate biological activity and could serve as leads for further optimizations for antivirus research.

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