Indoloprodigiosins from the C-10 bipyrrolic precursor: New antiproliferative prodigiosin analogs

Bioorganic & Medicinal Chemistry Letters
2006.0

Abstract

The condensation of the C-10 methoxybipyrrole precursor (3) of prodigiosin with indoles and a related pyrrole derivative yields novel analogs of prodigiosin. Biological evaluation of these products revealed compounds that inhibit cancer cell proliferation from 50 nM to 50 microM.

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