Literature

Abstract

In a mouse model, ertapenem inhibited the anaerobic intestinal microflora and promoted overgrowth of enterococci, whereas imipenem-cilastatin had no effect on the indigenous microflora. Ertapenem, but not imipenem-cilastatin, promoted modest overgrowth of vancomycin-resistant enterococci when exposure occurred during treatment. Neither agent promoted colonization with extended-spectrum beta-lactamase-producing Klebsiella pneumoniae.

DOI： 10.1128/aac.00355-06

Effect of Carbapenem Administration on Establishment of Intestinal Colonization by Vancomycin-Resistant Enterococci and Klebsiella pneumoniae in Mice

Antimicrobial Agents and Chemotherapy 2007.0

Effects of Imipenem-Cilastatin, Ertapenem, Piperacillin-Tazobactam, and Ceftriaxone Treatments on Persistence of Intestinal Colonization by Extended-Spectrum-β-Lactamase-Producing Klebsiella pneumoniae Strains in Mice

Antimicrobial Agents and Chemotherapy 2007.0

Bactericidal Activities of Meropenem and Ertapenem against Extended-Spectrum-β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae in a Neutropenic Mouse Thigh Model

Antimicrobial Agents and Chemotherapy 2007.0

In Vitro Activities of Doripenem and Six Comparator Drugs against 423 Aerobic and Anaerobic Bacterial Isolates from Infected Diabetic Foot Wounds

Antimicrobial Agents and Chemotherapy 2008.0

In VivoEfficacy of Simulated Human Dosing Regimens of Prolonged-Infusion Doripenem against Carbapenemase- ProducingKlebsiella pneumoniae

Antimicrobial Agents and Chemotherapy 2010.0

Susceptibility of Gram-Negative Pathogens Isolated from Patients with Complicated Intra-Abdominal Infections in the United States, 2007-2008: Results of the Study for Monitoring Antimicrobial Resistance Trends (SMART)