Overexpression and Initial Characterization of the Chromosomal Aminoglycoside 3′- O -Phosphotransferase APH(3′)-IIb from Pseudomonas aeruginosa

Overexpression and Initial Characterization of the Chromosomal Aminoglycoside 3′- O -Phosphotransferase APH(3′)-IIb from Pseudomonas aeruginosa Aph(3′)-IIc, an Aminoglycoside Resistance Determinant from Stenotrophomonas maltophilia The use of neamine as a molecular template: Inactivation of bacterial antibiotic resistance enzyme aminoglycoside 3′-phosphotransferase type IIa Mutant APH(2″)-IIa Enzymes with Increased Activity against Amikacin and Isepamicin Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids. Structural basis for the substrate recognition of aminoglycoside 7′′-phosphotransferase-Ia from <i>Streptomyces hygroscopicus</i> Nucleotide Selectivity of Antibiotic Kinases Acquisition of a Transposon Encoding Extended-Spectrum β-Lactamase SHV-12 by Pseudomonas aeruginosa Isolates during the Clinical Course of a Burn Patient Gene cluster for streptomycin biosynthesis in Streptomyces griseus: Analysis of a central region including the major resistance gene AAC(6′)-Iaf, a Novel Aminoglycoside 6′- N -Acetyltransferase from Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates