Multistep Resistance Selection and Postantibiotic-Effect Studies of the Antipneumococcal Activity of LBM415 Compared to Other Agents

Multistep Resistance Selection and Postantibiotic-Effect Studies of the Antipneumococcal Activity of LBM415 Compared to Other Agents In Vivo Characterization of the Peptide Deformylase Inhibitor LBM415 in Murine Infection Models Reduced Susceptibility of Haemophilus influenzae to the Peptide Deformylase Inhibitor LBM415 Can Result from Target Protein Overexpression Due to Amplified Chromosomal def Gene Copy Number Identification of novel potent bicyclic peptide deformylase inhibitors Hydroxamic Acid Derivatives as Potent Peptide Deformylase Inhibitors and Antibacterial Agents Peptide deformylase inhibitors with activity against respiratory tract pathogens Capability of 11 Antipneumococcal Antibiotics To Select for Resistance by Multistep and Single-Step Methodologies Synthesis, antibacterial activity, and biological evaluation of formyl hydroxyamino derivatives as novel potent peptide deformylase inhibitors against drug-resistant bacteria Antistaphylococcal Activity of CG400549, a New Experimental FabI Inhibitor, Compared with That of Other Agents In Vitro Activities of the Lipopeptides Palmitoyl (Pal)-Lys-Lys-NH ₂ and Pal-Lys-Lys Alone and in Combination with Antimicrobial Agents against Multiresistant Gram-Positive Cocci