Discovery of novel phosphorus-containing steroids as selective glucocorticoid receptor antagonist

Discovery of novel phosphorus-containing steroids as selective glucocorticoid receptor antagonist Discovery of non-steroidal mifepristone mimetics: Pyrazoline-based PR antagonists Discovery of a Potent Steroidal Glucocorticoid Receptor Antagonist with Enhanced Selectivity against the Progesterone and Androgen Receptors (OP-3633) 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity Synthesis and identification of novel oxa-steroids as progesterone receptor antagonists Synthesis and antihormonal properties of novel 11β-benzoxazole-substituted steroids Identification of the Clinical Candidate (R)-(1-(4-Fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CORT125134): A Selective Glucocorticoid Receptor (GR) Antagonist Parallel synthesis and SAR study of novel oxa-steroids as potent and selective progesterone receptor antagonists Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101) Synthesis and identification of novel 11β-aryl-4′,5′-dihydrospiro[estra-4,9-diene-17β,4′-oxazole] analogs with dissociated antiprogesterone activities