Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives

Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives Discovery of 1,3-diethyl-7-methyl-8-(phenoxymethyl)-xanthine derivatives as novel adenosine A 1 and A 2A receptor antagonists Discovery of benzothiazole-based adenosine A2B receptor antagonists with improved A2A selectivity (E)-1,3-Dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists 2-Aminothienopyridazines as Novel Adenosine A₁Receptor Allosteric Modulators and Antagonists C2-substituted quinazolinone derivatives exhibit A1 and/or A2A adenosine receptor affinities in the low micromolar range Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A_2AAdenosine Receptor Inverse Agonists with Antinociceptive Activity Mesoionic xanthine analogs: antagonists of adenosine receptors Synthesis and Structure−Activity Relationships of 3,7-Dimethyl-1-propargylxanthine Derivatives, A_2A-Selective Adenosine Receptor Antagonists Discovery of Potent and Highly Selective A_2BAdenosine Receptor Antagonist Chemotypes