Antihypertensive Activity of 6-O-Galloyl-D-glucose, a Phenolic Glycoside from Sapium sebiferum

Journal of Natural Products
1994.0

Abstract

The antihypertensive activity of a phenolic glycoside contained in the leaves of Sapium sebiferum was investigated. From intravenous screening using spontaneously hypertensive rats, 6-O-galloyl-D-glucose was identified as an active substance. The hypotensive action of this compound appears to be produced by an inhibition of noradrenaline release and/or a direct vasodilatation.

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