Protein-Tyrosine Kinase Inhibition: Mechanism-Based Discovery of Antitumor Agents

Protein-Tyrosine Kinase Inhibition: Mechanism-Based Discovery of Antitumor Agents Natural products as important tyrosine kinase inhibitors Naturally Occurring Homoisoflavonoids Function as Potent Protein Tyrosine Kinase Inhibitors by c-Src-Based High-Throughput Screening The association between anti-tumor potency and structure-activity of protein-kinases inhibitors based on quinazoline molecular skeleton Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors Structure-Based Discovery of Small Molecule Inhibitors Targeted to Protein Tyrosine Phosphatase 1B The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian α-carbonic anhydrase isoforms Antitumor studies – Part 2: Structure–activity relationship study for flavin analogs including investigations on their in vitro antitumor assay and docking simulation into protein tyrosine kinase Antitumor Agents 268. Design, Synthesis, and Mechanistic Studies of New 9-Substituted Phenanthrene-Based Tylophorine Analogues as Potent Cytotoxic Agents Novel Potent Orally Active Multitargeted Receptor Tyrosine Kinase Inhibitors: Synthesis, Structure−Activity Relationships, and Antitumor Activities of 2-Indolinone Derivatives