Synthesis and antiproliferative activity of unnatural enantiomers of 7-epi-goniofufurone and crassalactone C

Bioorganic & Medicinal Chemistry Letters
2008.0

Abstract

A facile synthesis of 7-epi-(-)-goniofufurone as well as the first synthesis of (-)-crassalactone C was achieved starting from D-xylose. A comparison of their in vitro antitumour activities with those observed for the corresponding naturally occurring enantiomers was provided.

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