Synthesis and antitumor activity of novel amsacrine analogs: The critical role of the acridine moiety in determining their biological activity

Synthesis and antitumor activity of novel amsacrine analogs: The critical role of the acridine moiety in determining their biological activity Potential antitumor agents. 47. 3'-Methylamino analogs of amsacrine with in vivo solid tumor activity Potential antitumor agents. 48. 3'-Dimethylamino derivatives of amsacrine: redox chemistry and in vivo solid tumor activity Potential antitumor agents. Part 38. 3-Substituted 5-carboxamido derivatives of amsacrine Potential antitumor agents. 40. Orally active 4,5-disubstituted derivatives of amsacrine Potential antitumor agents. 41. Analogs of amsacrine with electron-donor substituents in the anilino ring Synthesis and evaluation of anticancer activity of new 9-acridinyl amino acid derivatives Potential antitumor agents. 52. Carbamate analogs of amsacrine with in vivo activity against multidrug-resistant P388 leukemia Potential antitumor agents. 39. Anilino ring geometry of amsacrine and derivatives: relationship to DNA binding and antitumor activity 9-Substituted acridine derivatives with long half-life and potent antitumor activity: synthesis and structure-activity relationships