Structure-based hybridization of the bioactive natural products rhizonin A and ternatin leading to a selective fat-accumulation inhibitor against 3T3-L1 adipocytes

Structure-based hybridization of the bioactive natural products rhizonin A and ternatin leading to a selective fat-accumulation inhibitor against 3T3-L1 adipocytes (−)-Ternatin, a highly N-methylated cyclic heptapeptide that inhibits fat accumulation: structure and synthesis Convergent synthesis and in vivo inhibitory effect on fat accumulation of (−)-ternatin, a highly N-methylated cyclic peptide Whole Structure−Activity Relationships of the Fat-Accumulation Inhibitor (−)-Ternatin: Recognition of the Importance of Each Amino Acid Residue Design, synthesis, and biological evaluation of biotin-labeled (−)-ternatin, a potent fat-accumulation inhibitor against 3T3-L1 adipocytes Design, syntheses and lipid accumulation inhibitory activities of novel resveratrol mimics Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21 Synthesis and cytotoxic activity of acetogenin analogues Structure−Activity Relationship Study of Betulinic Acid, A Novel and Selective TGR5 Agonist, and Its Synthetic Derivatives: Potential Impact in Diabetes Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222