Pyranonaphthoquinone Lactones: A New Class of AKT Selective Kinase Inhibitors Alkylate a Regulatory Loop Cysteine

Pyranonaphthoquinone Lactones: A New Class of AKT Selective Kinase Inhibitors Alkylate a Regulatory Loop Cysteine Preparation and evaluation of deconstruction analogues of 7-deoxykalafungin as AKT kinase inhibitors Discovery of trans-3,4′-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers Identification of a novel 3,5-disubstituted pyridine as a potent, selective, and orally active inhibitor of Akt1 kinase N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα) Synthesis and structure–activity relationship of 3,4′-bispyridinylethylenes: Discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer Synthetic sulfoglycolipids targeting the serine–threonine protein kinase Akt Synthesis and cytotoxicity of pyranonaphthoquinone natural product analogues under bioreductive conditions Bioactive Quinolactacins and Structurally Related Pyrroloquinolones