Exploring the PI3Kα and γ binding sites with 2,6-disubstituted isonicotinic derivatives

Exploring the PI3Kα and γ binding sites with 2,6-disubstituted isonicotinic derivatives Synthesis and biological evaluation of pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine derivatives as novel PI3 kinase p110α inhibitors Synthesis of Phosphatidylinositol 3-Kinase (PI3K) Inhibitory Analogues of the Sponge Meroterpenoid Liphagal Discovery and bioactivity of 4-(2-arylpyrido[3′,2′:3,4]pyrrolo[1,2-f][1,2,4]triazin-4-yl) morpholine derivatives as novel PI3K inhibitors Preparation and evaluation of trisubstituted pyrimidines as phosphatidylinositol 3-kinase inhibitors. 3-Hydroxyphenol analogues and bioisosteric replacements Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110α inhibitors Design, Synthesis, and Biological Evaluation of Substituted Pyrimidines as Potential Phosphatidylinositol 3-Kinase (PI3K) Inhibitors Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design Discovery of novel morpholino–quinoxalines as PI3Kα inhibitors by pharmacophore-based screening Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases