Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ

Bioorganic & Medicinal Chemistry Letters
2009.0

Abstract

3-Methoxybenzamide is a weak inhibitor of the essential bacterial cell division protein FtsZ. Exploration of the structure-activity relationships of 3-methoxybenzamide analogues led to the identification of potent anti-staphylococcal compounds.

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