Synthesis and antimicrobial activity of new 1-alkyl/cyclohexyl-3,3-diaryl-1′-methylspiro[azetidine-2,3′-indoline]-2′,4-diones

European Journal of Medicinal Chemistry
2009.0

Abstract

The paper describes the synthesis of new 1-alkyl/cyclohexyl-3,3-diaryl-1'-methylspiro[azetidine-2,3'-indoline]-2',4-diones from the reactions of the 2-diazo-1,2-diarylethanones with 1-methyl-3-(alkyl/cyclohexylimino)indolin-2-ones under thermal condition. The compounds, characterized by satisfactory analytical and spectral (IR, (1)H NMR and (13)C NMR) data, have been screened for their antibacterial and antifungal activities.

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