Synthesis and Biological Activities of Thio-avarol Derivatives

Journal of Natural Products
2008.0

Abstract

Eleven new thio-avarol derivatives (3-13) were synthesized. Their antimicrobial, brine shrimp lethality, and free-radical scavenging activities and acetylcholinesterase inhibition, together with 12 already reported semisynthetic thio-avarol derivatives (14-25), were evaluated. Structure-activity relationships among these thio derivatives were determined.

Knowledge Graph

Similar Paper