Discovery of Dermorphin-Based Affinity Labels with Subnanomolar Affinity for Mu Opioid Receptors

Discovery of Dermorphin-Based Affinity Labels with Subnanomolar Affinity for Mu Opioid Receptors Synthesis and activity profiles of new dermorphin-(1-4) peptide analogs Dermorphin and deltorphin heptapeptide analogues: replacement of Phe residue by Dmp greatly improves opioid receptor affinity and selectivity Superpotent [Dmt¹]Dermorphin Tetrapeptides Containing the 4-Aminotetrahydro-2-benzazepin-3-one Scaffold with Mixed μ/δ Opioid Receptor Agonistic Properties Structure-activity studies of dermorphin. Synthesis and some pharmacological data of dermorphin and its 1-substituted analogs A photoaffinity reagent to label the opiate receptors of guinea pig ileum and mouse vas deferens Synthesis and binding activity of endomorphin-1 analogues containing β-amino acids Dermorphin tetrapeptide analogues with 2′,6′-dimethylphenylalanine (Dmp) substituted for aromatic amino acids have high μ opioid receptor binding and biological activities1 Potential affinity labels for the opiate receptor based on fentanyl and related compounds Dermorphin analogs carrying an increased positive net charge in their "message" domain display extremely high .mu.-opioid receptor selectivity