Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine

Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine The mimics of N ε -acyl-lysine derived from cysteine as sirtuin inhibitors Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model Novel acridinedione derivatives: Design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies Discovery of Dihydro-1,4-Benzoxazine Carboxamides as Potent and Highly Selective Inhibitors of Sirtuin-1 Identification of 2-hydroxybenzoic acid derivatives as selective SIRT5 inhibitors Synthesis of indole inhibitors of silent information regulator 1 (SIRT1), and their evaluation as cytotoxic agents A bicyclic pentapeptide-based highly potent and selective pan-SIRT1/2/3 inhibitor harboring Nε-thioacetyl-lysine Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2 Design, synthesis and structure–activity relationship studies of novel sirtuin 2 (SIRT2) inhibitors with a benzamide skeleton