Novel 3-Arylideneindolin-2-ones as Inhibitors of NAD⁺-Dependent Histone Deacetylases (Sirtuins)

Novel 3-Arylideneindolin-2-ones as Inhibitors of NAD⁺-Dependent Histone Deacetylases (Sirtuins) Functionalized tetrahydro-1H-pyrido[4,3-b]indoles: A novel chemotype with Sirtuin 2 inhibitory activity Identification and characterization of novel sirtuin inhibitor scaffolds Adenosine Mimetics as Inhibitors of NAD⁺-Dependent Histone Deacetylases, from Kinase to Sirtuin Inhibition 2-Aroylindoles and 2-Aroylbenzofurans with N-Hydroxyacrylamide Substructures as a Novel Series of Rationally Designed Histone Deacetylase Inhibitors Discovery and Characterization of R/S-N-3-Cyanophenyl-N′-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure–Activity Relationship Study Peptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors Structure–Activity Studies on Splitomicin Derivatives as Sirtuin Inhibitors and Computational Prediction of Binding Mode Novel acridinedione derivatives: Design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies