Synthesis and biological activities of some N-hydroxymethylene and N-methoxymethylene thiazines

Medicinal Chemistry Research
2007.0

Abstract

A series of new 3,5-diaryl-N-hydroxymethylene-1,4-thiazine-1,1-dioxides and 3,5-diaryl-N-methoxymethylene-tetrahydro-1,4-thiazines-1,1-dioxides were synthesized and their antimicrobial activities were tested against Gram-positive (Bacillus subtilis, Streptococci) and Gram-negative bacteria (Escherichia coli and Klebsiella penumoniae) and against the fungi Penicillium inclobium and Aspergillus flavus. The synthesized compounds have been characterized on the basis of elemental analyses, infrared spectroscopy (IR), and nuclear magnetic resonance (NMR).

Knowledge Graph

Similar Paper

Synthesis and biological activities of some N-hydroxymethylene and N-methoxymethylene thiazines
Medicinal Chemistry Research 2007.0
Synthesis, Nematicidal and Antimicrobial Properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2<i>H</i>-pyrazolo[3,4-<i>d</i>]thiazol-5-yl]phenyl]methanes
CHEMICAL & PHARMACEUTICAL BULLETIN 2009.0
Synthesis and physiological evaluation of new N-nitroso-2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxides
Medicinal Chemistry Research 2012.0
Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2,4-disubstituted thiazole ring
European Journal of Medicinal Chemistry 2010.0
Synthesis and antimicrobial screening of 5-(benzylidene)-3-phenylthiazolidin-4-one derivatives incorporating thiazole ring
Medicinal Chemistry Research 2013.0
Synthesis and antimicrobial activity of 5-((3-aryl-1-phenyl-1H-pyrazol-4-yl)methylene)thiazolidine-2,4-diones
Medicinal Chemistry Research 2012.0
Synthesis and biological evaluation of 5,7-diaryl-4,4-dimethyl-4,5,6,7-tetrahydropyridino[3,4-d]-1,2,3-thiadiazoles
Medicinal Chemistry Research 2007.0
Synthesis and antimicrobial evaluation of novel ethyl 2-(2-(4-substituted)acetamido)-4-subtituted-thiazole-5-carboxylate derivatives
Bioorganic & Medicinal Chemistry Letters 2016.0
Synthesis and antimicrobial activity of some new thiazole, thiophene and pyrazole derivatives containing benzothiazole moiety
European Journal of Medicinal Chemistry 2010.0
Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: Synthesis and biological evaluation as potential antibacterial and antifungal agents
Bioorganic & Medicinal Chemistry Letters 2006.0