Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs)

Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs) Discovery of potent anti-inflammatory 4-(4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-yl) pyrimidin-2-amines for use as Janus kinase inhibitors Design, synthesis and structure-activity relationship study of aminopyridine derivatives as novel inhibitors of Janus kinase 2 Discovery of novel selective Janus kinase 2 (JAK2) inhibitors bearing a 1H-pyrazolo[3,4-d]pyrimidin-4-amino scaffold Design, synthesis and preliminary biological evaluation of 4-aminopyrazole derivatives as novel and potent JAKs inhibitors Application of Sequential Palladium Catalysis for the Discovery of Janus Kinase Inhibitors in the Benzo[c]pyrrolo[2,3-h][1,6]naphthyridin-5-one (BPN) Series Design, Synthesis, and Antitumor Evaluation of 4-Amino-(1H)-pyrazole Derivatives as JAKs Inhibitors Discovery of imidazopyrrolopyridines derivatives as novel and selective inhibitors of JAK2 Benzimidazole Derivatives as Potent JAK1-Selective Inhibitors From Imidazoles to Pyrimidines:  New Inhibitors of Cytokine Release