Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis

Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity Pharmacophore modeling and structure-based virtual screening for a novel “switch region” target of bacterial RNA polymerase Molecular Docking Suggests the Targets of Anti-Mycobacterial Natural Products Discovery of Novel Nitrobenzothiazole Inhibitors for Mycobacterium tuberculosis ATP Phosphoribosyl Transferase (HisG) through Virtual Screening Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: Kinetic and structural studies Discovery of biphenyls bearing thiobarbiturate fragment by structure-based strategy as Mycobacterium tuberculosis protein tyrosine phosphatase B inhibitors Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery Identification and development of 2-methylimidazo[1,2-a]pyridine-3-carboxamides as Mycobacterium tuberculosis pantothenate synthetase inhibitors