Discovery and structure–activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor

Discovery and structure–activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 3: Structure-activity relationships of pyrropyrazolone derivatives Discovery and Structure Relationships of Salicylanilide Derivatives as Potent, Non-acidic P2X1 Receptor Antagonists Discovery of Novel 2,5-Dioxoimidazolidine-Based P2X₇Receptor Antagonists as Constrained Analogues of KN62 Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease The discovery and preclinical characterization of 6-chloro- N -(2-(4,4-difluoropiperidin-1-yl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)quinoline-5-carboxamide based P2X7 antagonists Antagonists of the P2X₇Receptor. From Lead Identification to Drug Development N-Substituted Phenoxazine and Acridone Derivatives: Structure–Activity Relationships of Potent P2X4 Receptor Antagonists Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells Therapeutic potentials and structure-activity relationship of 1,3-benzodioxole N-carbamothioyl carboxamide derivatives as selective and potent antagonists of P2X4 and P2X7 receptors