The KQ Element, a Complex Genetic Region Conferring Transferable Resistance to Carbapenems, Aminoglycosides, and Fluoroquinolones in Klebsiella pneumoniae

Antimicrobial Agents and Chemotherapy
2008.0

Abstract

The bla(KPC-3) and qnrB19 determinants of transferable Klebsiella pneumoniae plasmid pLRM24 reside within a complex region consisting of a Tn1331 backbone into which a Tn4401-like element and qnrB19 mobilized by an adjacent ISEcp1 insertion sequence have been inserted. This novel element represents a coalescence of genes conferring multidrug resistance in K. pneumoniae.

Knowledge Graph

Similar Paper

The KQ Element, a Complex Genetic Region Conferring Transferable Resistance to Carbapenems, Aminoglycosides, and Fluoroquinolones in Klebsiella pneumoniae
Antimicrobial Agents and Chemotherapy 2008.0
Presence of Plasmid-Mediated Quinolone Resistance in Klebsiella pneumoniae Isolates Possessing bla <sub>KPC</sub> in the United States
Antimicrobial Agents and Chemotherapy 2008.0
IS Ecp1 -Mediated Transposition of qnrB -Like Gene in Escherichia coli
Antimicrobial Agents and Chemotherapy 2008.0
Complete Nucleotide Sequence of Klebsiella pneumoniae Multidrug Resistance Plasmid pKP048, Carrying bla <sub>KPC-2</sub> , bla <sub>DHA-1</sub> , qnrB4 , and armA
Antimicrobial Agents and Chemotherapy 2010.0
Plasmid-Mediated qnrB2 and Carbapenemase Gene bla <sub>KPC-2</sub> Carried on the Same Plasmid in Carbapenem-Resistant Ciprofloxacin-Susceptible Enterobacter cloacae Isolates
Antimicrobial Agents and Chemotherapy 2008.0
Genetic Organization of Transposase Regions Surrounding bla <sub>KPC</sub> Carbapenemase Genes on Plasmids from Klebsiella Strains Isolated in a New York City Hospital
Antimicrobial Agents and Chemotherapy 2009.0
Characterization of the Plasmid-Borne Quinolone Resistance Gene qnrB19 in S almonella enterica Serovar Typhimurium
Antimicrobial Agents and Chemotherapy 2009.0
Genetic Structures at the Origin of Acquisition of the β-Lactamase bla <sub>KPC</sub> Gene
Antimicrobial Agents and Chemotherapy 2008.0
Association of QnrB Determinants and Production of Extended-Spectrum β-Lactamases or Plasmid-Mediated AmpC β-Lactamases in Clinical Isolates of Klebsiella pneumoniae
Antimicrobial Agents and Chemotherapy 2007.0
Novel Genetic Environment of the Carbapenem-Hydrolyzing β-Lactamase KPC-2 among Enterobacteriaceae in China
Antimicrobial Agents and Chemotherapy 2009.0