Emergence of Quinolone-Resistant Bordetella pertussis in Japan

Antimicrobial Agents and Chemotherapy
2009.0

Abstract

Six Bordetella pertussis strains isolated from children in Japan from 2004 to 2006 showed high-level resistance to nalidixic acid (NAL; MIC, >256 microg/ml) and decreased susceptibilities to fluoroquinolones. All of the NAL-resistant strains had the same D87G mutation in gyrA.

DOI： 10.1128/aac.00023-09

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