oqxAB Encoding a Multidrug Efflux Pump in Human Clinical Isolates of Enterobacteriaceae

Antimicrobial Agents and Chemotherapy
2009.0

Abstract

The genes for multidrug efflux pump OqxAB, which is active on fluoroquinolones, were found in human clinical isolates on a plasmid in Escherichia coli and on the chromosome of Klebsiella pneumoniae. IS26-like sequences flanked the plasmid-mediated oqxAB genes, suggesting that they had been mobilized as part of a composite transposon.

Knowledge Graph

Similar Paper

oqxAB Encoding a Multidrug Efflux Pump in Human Clinical Isolates of Enterobacteriaceae
Antimicrobial Agents and Chemotherapy 2009.0
Prevalence and Dissemination of oqxAB in Escherichia coli Isolates from Animals, Farmworkers, and the Environment
Antimicrobial Agents and Chemotherapy 2010.0
Plasmid-Mediated Quinolone Resistance Pump QepA2 in an Escherichia coli Isolate from France
Antimicrobial Agents and Chemotherapy 2008.0
New Plasmid-Mediated Fluoroquinolone Efflux Pump, QepA, Found in an Escherichia coli Clinical Isolate
Antimicrobial Agents and Chemotherapy 2007.0
Plasmid-Mediated qnrB2 and Carbapenemase Gene bla <sub>KPC-2</sub> Carried on the Same Plasmid in Carbapenem-Resistant Ciprofloxacin-Susceptible Enterobacter cloacae Isolates
Antimicrobial Agents and Chemotherapy 2008.0
Transferable Resistance to Aminoglycosides by Methylation of G1405 in 16S rRNA and to Hydrophilic Fluoroquinolones by QepA-Mediated Efflux in Escherichia coli
Antimicrobial Agents and Chemotherapy 2007.0
First Detection of Plasmid-Encoded bla <sub>OXY</sub> β-Lactamase
Antimicrobial Agents and Chemotherapy 2009.0
Presence of Plasmid-Mediated Quinolone Resistance in Klebsiella pneumoniae Isolates Possessing bla <sub>KPC</sub> in the United States
Antimicrobial Agents and Chemotherapy 2008.0
IS Ecp1 -Mediated Transposition of qnrB -Like Gene in Escherichia coli
Antimicrobial Agents and Chemotherapy 2008.0
Characterization of pABVA01, a Plasmid Encoding the OXA-24 Carbapenemase from Italian Isolates of Acinetobacter baumannii
Antimicrobial Agents and Chemotherapy 2009.0