3,5-Disubstituted-indole-7-carboxamides: The discovery of a novel series of potent, selective inhibitors of IKK-β

3,5-Disubstituted-indole-7-carboxamides: The discovery of a novel series of potent, selective inhibitors of IKK-β IKKβ inhibitors identification part I: Homology model assisted structure based virtual screening Novel IKKβ inhibitors discovery based on the co-crystal structure by using binding-conformation-based and ligand-based method Structure-based design and biological profile of (E)-N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of IκB kinase-β Novel IKK inhibitors: β-carbolines Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 2: Improvement of in vitro activity Pharmacophore modeling and virtual screening studies for new VEGFR-2 kinase inhibitors Discovery and Structure−Activity Relationship of 3-Aminopyrid-2-ones as Potent and Selective Interleukin-2 Inducible T-Cell Kinase (Itk) Inhibitors Pharmacophore modeling and virtual screening for the discovery of new transforming growth factor-β type I receptor (ALK5) inhibitors Virtual Screening to Successfully Identify Novel Janus Kinase 3 Inhibitors: A Sequential Focused Screening Approach