Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity

Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78 Biological Evaluation of 5′-(N-Ethylcarboxamido)adenosine Analogues as Grp94-Selective Inhibitors Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70 Resorcinol-Based Grp94-Selective Inhibitors Adenine derived inhibitors of the molecular chaperone HSP90—SAR explained through multiple X-ray structures Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold Discovery of small molecules targeting GRP78 for antiangiogenic and anticancer therapy ATPases as Drug Targets: Insights from Heat Shock Proteins 70 and 90