Synthesis and screening of ( E )-1-(β- d -galactopyranosyl)-4-(aryl)but-3-ene-2-one against Mycobacterium tuberculosis
Bioorganic & Medicinal Chemistry Letters
2011.0
Abstract
A series of galactose-derived aryl enones were synthesised and screened against Mycobacterium tuberculosis H(37)Rv. Preliminary results were promising with MIC values in the range 1.56-12.5 μg/mL.