Synthesis of New Vitamin K Analogues as Steroid and Xenobiotic Receptor (SXR) Agonists: Insights into the Biological Role of the Side Chain Part of Vitamin K

Synthesis of New Vitamin K Analogues as Steroid and Xenobiotic Receptor (SXR) Agonists: Insights into the Biological Role of the Side Chain Part of Vitamin K Synthesis of Novel Vitamin K₂ Analogues with Modification at the ω-Terminal Position and Their Biological Evaluation as Potent Steroid and Xenobiotic Receptor (SXR) Agonists Chemistry of the new immunosuppressant KH-1060: new synthons and x-ray evidence for unique side-chain geometry Modeling, Synthesis and Biological Evaluation of Potential Retinoid X Receptor (RXR) Selective Agonists: Novel Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential 3-(3-Aryloxyaryl)imidazo[1,2-a]pyridine sulfones as liver X receptor agonists Side-Chain Modified Ergosterol and Stigmasterol Derivatives as Liver X Receptor Agonists Synthesis of 4-(3-biaryl)quinoline sulfones as potent liver X receptor agonists Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol Structure–Activity Relationship Study of Vitamin K Derivatives Yields Highly Potent Neuroprotective Agents