Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase

Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase Peptidyl-urea based inhibitors of soluble epoxide hydrolases Design, synthesis and biological evaluation of 4-(1-(4(sulphanilamide)phenyl)-3-(methyl)-1H-pyrazol-5-yl)dine urea and N-acyl derivatives as a soluble epoxide hydrolase inhibitors Novel soluble epoxide hydrolase inhibitors with a dihydropyrimidinone scaffold: design, synthesis and biological evaluation Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase 1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure−Activity Relationships, Pharmacokinetics, and Reduction of Inflammatory Pain Discovery of a Highly Potent, Selective, and Bioavailable Soluble Epoxide Hydrolase Inhibitor with Excellent Ex Vivo Target Engagement Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors Incorporation of Piperazino Functionality into 1,3-Disubstituted Urea as the Tertiary Pharmacophore Affording Potent Inhibitors of Soluble Epoxide Hydrolase with Improved Pharmacokinetic Properties Discovery of enantioselectivity of urea inhibitors of soluble epoxide hydrolase