Design, synthesis and biological evaluation of novel indano- and thiaindano-pyrazoles with potential interest for Alzheimer's disease

MedChemComm
2013.0

Abstract

The synthesis of eighteen novel (thia)indanopyrazole derivatives was achieved starting from amino(thia) indanones. Some of them displayed a dual binding site acetylcholinesterase inhibition which makes them potentially interesting for Alzheimer's disease treatment.

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