Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections Design and synthesis of potent Gram-negative specific LpxC inhibitors Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections Design, Synthesis, and Properties of a Potent Inhibitor ofPseudomonas aeruginosaDeacetylase LpxC Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa Inhibition of the Antibacterial Target UDP-(3-O-acyl)-N-acetylglucosamine Deacetylase (LpxC):  Isoxazoline Zinc Amidase Inhibitors Bearing Diverse Metal Binding Groups Optimization of LpxC Inhibitor Lead Compounds Focusing on Efficacy and Formulation for High Dose Intravenous Administration Hydroxamic Acid Derivatives as Potent Peptide Deformylase Inhibitors and Antibacterial Agents Novel inhibitors of bacterial two-component systems with gram positive antibacterial activity: Pharmacophore identification based on the screening hit closantel