Evaluation of FR901464 analogues in vitro and in vivo

Med. Chem. Commun.
2010.0

Abstract

This study was designed to determine the in vitro and in vivo antitumor behaviour of three analogues of the natural product FR901464. All analogues demonstrated effective inhibition of cell proliferation. Minimal in vivo antitumor activity was observed, warranting further PK and antitumor efficacy studies.

Knowledge Graph

Similar Paper