Synthesis and biological evaluation of novel anticancer bivalent colchicine–tubulizine hybrids

Synthesis and biological evaluation of novel anticancer bivalent colchicine–tubulizine hybrids Inhibitors of tubulin polymerization: Synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III Design, synthesis and biological evaluation of colchicine derivatives as novel tubulin and histone deacetylase dual inhibitors Synthesis of tetrazole–isoxazoline hybrids as a new class of tubulin polymerization inhibitors Design and Synthesis of Pironetin Analogue/Colchicine Hybrids and Study of Their Cytotoxic Activity and Mechanisms of Interaction with Tubulin Synthesis and biological evaluation of B-ring modified colchicine and isocolchicine analogs New Colchicine-Derived Triazoles and Their Influence on Cytotoxicity and Microtubule Morphology Synthesis and biological evaluation of cis -restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers Synthesis and mechanism of action of novel pyrimidinyl pyrazole derivatives possessing antiproliferative activity Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities