An Anthraquinone Scaffold for Putative, Two-Face Bim BH3 α-Helix Mimic

An Anthraquinone Scaffold for Putative, Two-Face Bim BH3 α-Helix Mimic Bcl-2/MDM2 Dual Inhibitors Based on Universal Pyramid-Like α-Helical Mimetics Synthesis and biological activities of new di- and trimeric quinoline derivatives Design, synthesis, and activity evaluation of broad-spectrum small-molecule inhibitors of anti-apoptotic Bcl-2 family proteins: Characteristics of broad-spectrum protein binding and its effects on anti-tumor activity Pro-apoptotic carboxamide analogues of natural fislatifolic acid targeting Mcl-1 and Bcl-2 Identification of novel bivalent mimetics of annonaceous acetogenins via a scaffold-hopping strategy Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin A Structure−Activity Relationship Studies of Phenanthridine-Based Bcl-X_L Inhibitors Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-X_L and BCL-2 Design and synthesis of de novo cytotoxic alkaloids through mimicking taxoid skeleton