Anti-microbial benzimidazole derivatives: synthesis and in vitro biological evaluation

Medicinal Chemistry Research
2012.0

Abstract

In this study, we have synthesized 5-(nitro/chloro)-2-styryl-benzimidazoles and evaluated for in vitro anti-microbial activity with different strain like anti-bacterial activity against Staphylococcus aureus, Escherichia coli, and anti-fungal activity against Candida albicans were carried out. Compounds 2, 4, 7, 8 showed higher activity against S. aureus, compounds 2, 8, 9, 10 showed higher activity against E. coli and Compounds 2, 7, 9, 8 showed higher activity against C. albicans.

Knowledge Graph

Similar Paper

Anti-microbial benzimidazole derivatives: synthesis and in vitro biological evaluation
Medicinal Chemistry Research 2012.0
Synthesis and evaluation of in vitro anti-microbial and anti-tubercular activity of 2-styryl benzimidazoles
European Journal of Medicinal Chemistry 2009.0
Synthesis and in vitro antimicrobial activity of some novel substituted benzimidazole derivatives having potent activity against MRSA
European Journal of Medicinal Chemistry 2009.0
Synthesis and biological evaluations of novel benzimidazoles as potential antibacterial agents
Bioorganic & Medicinal Chemistry Letters 2004.0
Synthesis and antimicrobial activity of some novel phenyl and benzimidazole substituted benzyl ethers
Bioorganic & Medicinal Chemistry Letters 2007.0
Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents
Bioorganic & Medicinal Chemistry 2007.0
Synthesis and biological activity of some new benzoxazoles
European Journal of Medicinal Chemistry 2008.0
Synthesis, physicochemical properties and antimicrobial activity of some new benzimidazole derivatives
European Journal of Medicinal Chemistry 2009.0
Synthesis and Antifungal Activity of 2-Chloromethyl-1H-benzimidazole Derivatives against Phytopathogenic Fungi in Vitro
Journal of Agricultural and Food Chemistry 2013.0
Convenient one-pot synthesis of novel 2-substituted benzimidazoles, tetrahydrobenzimidazoles and imidazoles and evaluation of their in vitro antibacterial and antifungal activities
European Journal of Medicinal Chemistry 2009.0