Synthesis and anti-inflammatory activity of 1-acetyl/propanoyl-5-aryl-3-(4-morpholinophenyl)-4,5-dihydro-1H-pyrazole derivatives

Medicinal Chemistry Research
2012.0

Abstract

A series of novel pyrazoline derivatives containing 4-morpholinophenyl moiety were synthesized to investigate their potential anti-inflammatory activity. The chemical structures of the compounds were elucidated by spectral data and element analyses. The test compounds in the series exhibited different levels of anti-inflammatory activities when compared with reference drug indomethacin.

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