QSAR STUDIES ON ADENOSINE KINASE INHIBITORS

Medicinal Chemistry Research
2004.0

Abstract

The present study reports QSAR study on adenosine kinase inhibitors pyrrolo[2, 3-d] pyrimidine nucleoside analogous. The equalized electronegativity along with a large pool of topological indices are used for the purpose. The regression analysis has shown that equalized electronegativity is a good parameter which in combination with topological indices and an indicator parameter gave excellent model.

Knowledge Graph

Similar Paper

QSAR STUDIES ON ADENOSINE KINASE INHIBITORS
Medicinal Chemistry Research 2004.0
QSAR study on adenosine kinase inhibition of pyrrolo[2,3- d ]pyrimidine nucleoside analogues using the hansch approach
Bioorganic & Medicinal Chemistry Letters 2002.0
A TOPS-MODE approach to predict adenosine kinase inhibition
Bioorganic & Medicinal Chemistry Letters 2004.0
A CoMSIA study on the adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues
Bioorganic & Medicinal Chemistry 2008.0
Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides
Bioorganic & Medicinal Chemistry Letters 2004.0
QSAR Study of Anticonvulsant Negative Allosteric Modulators of the AMPA Receptor
Journal of Medicinal Chemistry 2004.0
QSAR study on topically acting sulfonamides incorporating GABA moieties: A molecular connectivity approach
Bioorganic & Medicinal Chemistry Letters 2006.0
Adenosine Kinase Inhibitors. 1. Synthesis, Enzyme Inhibition, and Antiseizure Activity of 5-Iodotubercidin Analogues
Journal of Medicinal Chemistry 2000.0
Synthesis, pharmacological activity and comparative QSAR modeling of 1,5-N,N′-substituted-2-(substituted naphthalenesulphonyl) glutamamides as possible anticancer agents
European Journal of Medicinal Chemistry 2010.0
Quantitative structure–activity relationship (QSAR) of aryl alkenyl amides/imines for bacterial efflux pump inhibitors
European Journal of Medicinal Chemistry 2009.0