A study on the reactions of alkyl 4,6-bis(4-fluorophenyl)-2-oxocyclohex-3-ene-1-carboxylate and in vitro antioxidant activity of derivatives

Medicinal Chemistry Research
2013.0

Abstract

New functionalized derivatives were prepared using alkyl 4,6-bis(4-fluorophenyl)-2 oxocyclohex-3-ene-1-carboxylate as a building block. Newly prepared compounds were well characterized using 1 H NMR, IR, and mass spectral data. All the synthesized products were screened for their antioxidant properties. Among the tested compounds, indazole derivatives exhibited noticeable DPPH radical scavenging activity and reducing power capacity in comparison with the standard Glutathione.

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