Synthesis and antibacterial activity of some new hydrazones

Medicinal Chemistry Research
2013.0

Abstract

New hydrazone derivatives were synthesized by the condensation of some selected heteroaromatic hydrazines with appropriate aromatic ketones at high temperature (100 C). The structures of the synthesized compounds were established by elemental (CHN) and spectral (IR, 1 HNMR, and Mass) analysis. The synthesized compounds were screened for their antibacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Proteus mirabilis) activities, which reveal that all the compounds possess activity against all the tested organisms.

Knowledge Graph

Similar Paper

Synthesis and antibacterial activity of some new hydrazones
Medicinal Chemistry Research 2013.0
Novel pyridazine derivatives: Synthesis and antimicrobial activity evaluation
European Journal of Medicinal Chemistry 2009.0
Synthesis and antimicrobial activity studies of some novel substituted phenylhydrazono-1H-tetrazol-5-yl-acetonitriles
Medicinal Chemistry Research 2010.0
Synthesis and antibacterial, antifungal activities of some 2r,4c-diaryl-3-azabicyclo[3.3.1]nonan-9-one-4-aminobenzoyl hydrazones
Medicinal Chemistry Research 2012.0
Synthesis, characterization and antimicrobial activity of novel ethyl 1-(N-substituted)-5-phenyl-1H-pyrazole-4-carboxylate derivatives
Medicinal Chemistry Research 2012.0
Synthesis and evaluation of antimicrobial activity of hydrazones derived from 3-oxido-1H-imidazole-4-carbohydrazides
European Journal of Medicinal Chemistry 2013.0
Synthesis and study of 1-ethyl-3-carbohydrazide and 3-[1-oxo-2-hydrazino-3-{p-toluenesulfon}]quinolone derivatives against bacterial infections
European Journal of Medicinal Chemistry 2013.0
Synthesis and antimicrobial activity of some novel hydrazide, benzochromenone, dihydropyridine, pyrrole, thiazole and thiophene derivatives
European Journal of Medicinal Chemistry 2013.0
Synthesis, characterization, and biological evaluation of some N-aryl hydrazones and their 2,3-disubstituted-4-thiazolidinone derivatives
Medicinal Chemistry Research 2013.0
Antimicrobial activity and a SAR study of some novel benzimidazole derivatives bearing hydrazone moiety
European Journal of Medicinal Chemistry 2010.0