Synthesis and biological evaluation of 4-chlorocolchicine derivatives as potent anticancer agents with broad effective dosage ranges

Synthesis and biological evaluation of 4-chlorocolchicine derivatives as potent anticancer agents with broad effective dosage ranges 4-Chlorocolchicine derivatives bearing a thiourea side chain at the C-7 position as potent anticancer agents Design, Synthesis, and Antitumor Activity of 4-Halocolchicines and Their Pro-drugs Activated by Cathepsin B Synthesis, anticancer activity and molecular docking studies of N-deacetylthiocolchicine and 4-iodo-N-deacetylthiocolchicine derivatives Antitumor agents. Part 236: Synthesis of water-soluble colchicine derivatives Synthesis, antiproliferative activity, and molecular docking studies of 4‐chlorothiocolchicine analogues Recent developments on (−)-colchicine derivatives: Synthesis and structure-activity relationship 7-Deacetyl-10-alkylthiocolchicine derivatives – new compounds with potent anticancer and fungicidal activity Synthesis and antiproliferative screening of novel doubly modified colchicines containing urea, thiourea and guanidine moieties Biological effects of modified colchicines. 2. Evaluation of catecholic colchicines, colchifolines, colchicide, and novel N-acyl- and N-aroyldeacetylcolchicines